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NEW - Blue Shield will launch three PPO Savings Plans offering expanded weight loss drug coverage in 2027: Full PPO Savings Embedded Deductible 3400 100% with Enhanced+ Rx Full PPO Savings Two-Tier Embedded Deductible 1700/3400/3400 90/60 with Enhanced+ Rx NOTE: Weight loss drugs under these plans are covered with prior authorization for BMI 30 or 27 with certain weight-related conditions, lowering the requirement from the previous BMI of 40

What We Don't Know: No human clinical trials yet

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Neuroprotective effects of GLP-1R agonists GLP-1 and its mimetics can cross the BBB, therefore, are able to affect the CNS function such as cognition and neuroprotection (138)