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If nausea occurs, split the dose into smaller amounts taken throughout the day, or switch to a sustained-release NAC formulation

While uncommon, gallbladder problems may be more likely with higher doses and longer durations of use

HJ performed the data analysis and interpretation of the results, along with MAA (interpretation)

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To obtain purified plasmid standard DNA, PCR products were amplified with a mouse mtDNA-specific primer as previously described 18 , and were ligated into PMD-19T vector (Takara)