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Pathophysiological Mechanisms of Ocular Nutrition Oxidative Stress and Antioxidant Defense Systems The retinal environment, particularly the macula, exists under conditions of high oxidative stress due to intense light exposure, elevated oxygen consumption, and abundant polyunsaturated fatty acids

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Although not as extensively studied as the previously mentioned antioxidants, melatonin has been shown to exhibit protective effects against PM and ozone

doi: 10.1016/S0197-4580(00)00124-X 6 AllisonR

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