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National Library of Medicine, Accessed 20 Aug
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Very common side effects (affecting more than 1 in 10 people) include: Nausea often most pronounced when initiating treatment or increasing the dose Diarrhoea may be transient and typically improves with continued use Decreased appetite a therapeutic effect but may lead to inadequate nutrition if extreme Common side effects (affecting up to 1 in 10 people) include: Vomiting can contribute to dehydration if severe or persistent Constipation may occur as part of gastrointestinal effects Abdominal pain or discomfort usually mild and self-limiting Dyspepsia (indigestion) Fatigue may relate to reduced caloric intake or metabolic changes Injection site reactions redness, itching, or swelling at the injection site Hypoglycaemia particularly when Mounjaro is used in combination with insulin or sulfonylureas [1] [19] To minimise gastrointestinal side effects, the SmPC recommends starting at the lowest dose (2.5 mg weekly) and gradually titrating upwards every four weeks
The study populations with T2D The analyses on the associations of semaglutide with both incident and recurrent CUD among patients with T2D had a starting time of 12/2017 when semaglutide was approved in the US as Ozempic for treating T2D and an ending date of 5/2021 to allow us to separately examine the effects of semaglutide on CUD as Ozempic from those as Wegovy in the study population with obesity
The slowed gastric emptying they cause increases aspiration risk during anesthesia
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