2019;6:23 Mieszawska AJ, Mulder WJ, Fayad ZA, Cormode DP
Thus, the effect of DSIP on coping with acute and long-term stress largely depends on the changes in the levels of other oligopeptides and hormones that DSIP induces
The physiochemical properties of D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 were estimated following modeling with ADMET Predictor software
Glycyrrhizin inhibits the metabolism of diosbulbin B (Yang et al., 2024), promotes bile acid efflux by increasing the expression of Nrf2/Farnesoid X Receptor- Bile Salt Export Pump (FXR-BSEP)/Multidrug Resistance-Associated Protein (MRP)2/P-glycoprotein/UDP-glucuronosyltransferase 1A1(UGT1A1), modulates gut microbiota, alleviates inflammation and oxidative stress, and improves diosbulbin B-induced liver injury (Wang et al., 2025)
Complete loss of GPX4 is incompatible with viability, and pharmacological or genetic GPX4 inhibition is widely exploited to induce ferroptosis in cells and tissues