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Patients should start with a typical dose of 75 mg daily, adjusted by a healthcare provider based on response and tolerance

This included a tissue specificity test against differentially expressed genes (DEGs) across all 54 GTEx v8 tissues, with significance defined by a Bonferroni-corrected P-value 0.01 were included

using advanced analytical instrumentation

By investigating the effects of GLP-1 agonists on GSK3-Drp1 signalling, this study uncovered novel mechanisms by which these agents may confer mitochondrial protection and improve RV function in PH