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Alongside GLP-1 RAs, the DPP-4 inhibitors have been developed to exploit the incretin system by prolonging the duration of endogenous GLP-1 (Nauck and Meier, 2016)

To ensure timely access to affordable, safe and effective, high quality biosimilar treatment options, streamlined development must become the default regulatory expectation

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This results in lower blood sugar levels and ultimately leads to weight loss as confirmed by one of the clinical trials where subjects reported a 15% loss in body weight

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