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The human MTHFR protein comprises multiple domains, including an N-terminal catalytic domain, which houses a conserved serine-rich region, and a C-terminal regulatory domain (Figure 2)

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197 Collectively, these pleiotropic effects position GLP-1R agonists as promising therapeutic agents for improving cardiovascular outcomes, extending their benefits far beyond glycemic control

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Liraglutide 3.0 Mg and Intensive Behavioral Therapy (IBT) for Obesity in Primary Care: The SCALE IBT Randomized Controlled Trial