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Administration of finerenone could downregulate the expression of the proinflammatory cytokines IL-6 and IL-1 in the kidneys of bilateral ischemia-reperfusion-induced CKD in mice, and ameliorate inflammation and tubulointerstitial fibrosis

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Hepatic morphology analysis showed that GSTM2 -KO-livers formed more LDs than WT livers (Supplementary Fig