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Key drugs facing patent cliffs during this period include Keytruda (pembrolizumab) starting around 2028, Eliquis (apixaban) starting around 2026 to 2028 depending on PTE outcomes, Opdivo (nivolumab) starting around 2026, Xarelto (rivaroxaban) with varying international timelines, Jardiance (empagliflozin) with U.S

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Suspected side effects should be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)