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A cerebral MRI performed approximately 18 months later at another hospital for vague complaints of fatigue, was reported as normal indicating probable reversal of white matter changes seen in the first MRI

Moreover, treatment with the GLP-1R agonist affects the transcriptional regulation of GSK3 resulting in significant reduction and normalisation to wild-type levels

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A low FODMAP probiotic and prebiotic can also be beneficial in managing gut health, which is often compromised in PCOS