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Beyond its role as a glutathione precursor, NAC has unique benefits, such as: Respiratory support : NAC helps thin mucus and improve lung function Neuroprotection : It influences glutamate regulation in the brain, which may support mood and cognitive health Detoxification : NAC directly binds to certain toxins, making them less harmful Antioxidant activity : NAC can directly scavenge free radicals, though less potently than glutathione itself Key Distinction In short: Glutathione = the end product , the bodys main antioxidant and detox molecule

doi: 10.1186/s13045-024-01559-0 Summary Keywords cancer therapy, ferroptosis, immunometabolism, iron homeostasis, redox signaling, tumor-associated macrophages Citation Qian Z, Zhang Z, Bai W, Li J, Rao X, Huang G, Liu J and Wei W (2026) Immunometabolic crosstalk between tumor- associated macrophages and ferroptotic cancer cells: mechanisms, regulation, and therapeutic applications

Pryor et al., 2019

tb burden, and granulomatous response in the lungs

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