glp-1 receptor function Agonists Glucagon-like peptide 1 (GLP-1) -

SGLT-2 inhibitors included dapagliflozin, empagliflozin, canagliflozin, ertugliflozin, and bexagliflozin

10.21037/atm-20-5307 60

Compounds 47 and 48 (Figure 6), with IC 50 values of 0.83 and 0.43 M, respectively, which possess aryl-substituted piperazines with acetamide linkers, showed the best activity as DPP-4 inhibitors

Compounded semaglutide is typically administered as a subcutaneous injection according to the directions provided by the prescribing clinician and the compounding pharmacys labeling

In conclusion, developing novel DPP-4 inhibitors based on halogenated scaffolds is a promising area of research