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Licensed pharmacological options such as orlistat and semaglutide (Wegovy, per NICE TA875) may be appropriate for eligible individuals

Nutrients (2023) 15:1880

Clinical trials show this cagrilintide semaglutide mix produces about 25% body weight reduction compared to 15-17% with semaglutide alone, showing clear combined benefits

In the second stage, sealed envelopes were used to further allocate participants into one of three groups: a single DPSC injection (1 10 cells/injection), a double DPSC injection (1 10 cells/injection, administered twice at a 30-day interval), or a saline injection