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These calculations are for education only and do not replace clinical advice, diagnosis, or treatment

People with obesity or overweight who took a daily Wegovy pill 25 milligrams of oral semaglutide for a year and three months lost 13.6% of their body weight on average, compared to 2.2% for those who took a placebo

Records of previous attempts at weight loss, including details about diet, exercise programs, or other treatments you've tried

The question is no longer whether GLP-1 receptor agonists work

The medications are GLP-1 receptor agonists, which mimic the effects of naturally occurring GLP-1 peptides produced in the gut