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In a randomized, placebo-controlled trial in overweight or obese pre-diabetic adults, a supplement containing cinnamon, chromium, and carnosine significantly reduced fasting plasma glucose and increased fat-free mass compared with placebo

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Research shows that many patients regain weight after discontinuing GLP-1 therapy, which raises questions about whether insurance should cover indefinite use

Restoring glutathione availability may lower oxidative burden, but clinical translation depends on concurrent micronutrient repletion (selenium, zinc, iron) and resolution of the primary inflammatory driver

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