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Further scientific research is needed to develop additional therapeutic approaches that enhance T cell-mediated tumor clearance by modulating ammonia levels

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KPV is the only one of the four that targets NF-B-driven cytokine production directly

This means: No human PK reference data No human bioavailability data No human metabolism or clearance data Rodent-to-human PK extrapolation is therefore speculative This is a major context for research framing