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Deodati A, et al

The most common problems in those trials were gastrointestinal (nausea, diarrhoea, constipation and vomiting), along with an unusual skin-sensitivity effect

Because tirzepatide was only approved by the FDA in mid-2022 for type 2 diabetes, the ability to rigorously analyze its use (on- and off-label) for a broad population of patients with overweight or obesity, not just a subset captured in insurance databases, has the power to greatly improve our understanding of how these agents are being used in everyday practice and the effect that theyre having. Consider individual factors when prescribing Tirzepatide was tied to greater weight loss than semaglutide, but providers should consider each person with obesitys circumstances when considering which medication to prescribe, according to Ni cholas L

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Check that out on Substack at hypermobilitymd.substack.com