IGF-1s positive effect on cognition appears to be dependent on maintaining balanced levels, with excessively high or low levels to be avoided
As more people use semaglutide, reports of unexpected side effects are growing: unpleasant changes to your skin and body shape, digestive problems, and unexpected fatigue (sometimes called GLP-1 fatigue.) I want to make you aware of these potential problems so you aren't caught off-guard and left holding your stomach and your head...and wondering why you suddenly look old and feel so tired if you opt for a GLP-1 drug
10.1016/j.abb.2008.03.008 Arch
In addition, conditions such as pregnancy, eating disorders, pancreatitis history, cardiovascular disease, and substance use disorders may affect which medications are safe to use
In the placebo-controlled studies, STEP 1 to STEP 4, SAEs occurred in 8% to 10% of patients in the semaglutide group and 3% to 9% of patients in the placebo group (Table 36 and Table 37)