itching from semaglutide as a Side Effect of Semaglutide: Causes, Prevention, and Solutions Can Semaglutide Cause Skin Sensitivity?

They're following bro-science

Lancet (London, England), 376 (9741), 595605

It also suits users who already enjoy peptide facial serums and want similar formula aesthetics in body care

In vitro and in vivo models, knockout or inhibition of GPX4 can rapidly induce severe lipid peroxidation, mitochondrial rupture, and typical ferroptosis phenotypes in chondrocytes, further reinforcing its core role in maintaining joint homeostasis (Sun S

It belongs to a novel class of agents known as triple agonists , meaning it simultaneously activates three distinct hormone receptors: GIP receptor (glucose-dependent insulinotropic polypeptide) GLP-1 receptor (glucagon-like peptide-1) Glucagon receptor This triple mechanism of action distinguishes retatrutide from currently approved agents such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 agonist)