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On August 15, 2025, the FDA granted accelerated approval to Wegovy (semaglutide 2.4 mg) for treating adults with non-cirrhotic MASH and moderate to advanced liver fibrosis
9 The semaglutide group exhibited significant improvements in symptoms and physical limitations, assessed using the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS), with the change in KCCQ-CSS being the primary trial endpoint
Clean numbers at every standard dose point
Arulmozhi DK, Portha B
The inotropic effect: retatrutide makes your heart beat harder, not just faster Most discussions of retatrutide heart rate focus on the chronotropic effect, the increase in beats per minute
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