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Evidence comes mainly from animal models, with outcomes varying by sex, species, and experimental conditions

4 In rats subjected to dopamine receptor antagonism (haloperidol-induced catalepsy), BPC-157 administration produced significant recovery of motor function an effect attenuated by NOS inhibition

389 GSK-J1 is a specific JMJD3 inhibitor 390 that can affect the demethylation of histone H3K27me3, regulate Th17/Treg cell differentiation, suppress the secretion of inflammatory factors, and improve the intestinal mucosal immune dysfunction caused by DSS in experimental acute UC model mice

HIF-1-deficiency results in dysregulated EPO signaling and iron homeostasis in mouse development