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Therefore, EC and CH were marked as potential inhibitors of the murine tyrosinase enzyme by comparison to C3G

The artesunate resistance observed with 1804 M488I parasites was reduced in the presence of SFN, with parasite loads not significantly different from 1804 wt parasites treated with artesunate only (Fig 8A)

In a nutshell, this is where the various doses are: 90 iu = 9 units 100iu = 10 units 125iu= 12.5 units (as close as you can get to it- there will likely be a hashmark for 12 and 13 units- just do your best)

This treatment paradigm has been previously well characterized as a suitable animal model for tissue GSH depletion without cytotoxicity (53)

doi: 10.3390/life14111455 147 TohyamaCHondaY