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NICE guidance recommends formal assessment at six months, with continuation criteria including HbA1c reduction of at least 11 mmol/mol and weight loss of at least 3% where applicable

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4.5 Immune system Typically, during the last months of gestation and the first month of lactation, there is an increase in fat mobilization from maternal depots and an accumulation of hepatic non-esterified fatty acid (NEFA) (Pullen et al., 1990)