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Its chemical stability and non-toxic copper delivery capacity further underscore its utility as a molecular tool for investigating gene expression, tissue regeneration, and copper-mediated biochemical processes (Pickart, Vasquez-Soltero, and Margolina 2012)

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Moreover, the expression of key spermatogenesis markers, including UCHL1, PLZF, SCP3, and PCNA, which were reduced in aged testes, were significantly restored or increased following FOXO4-DRI treatment

However, this appetite suppression can also lead to a decrease in overall food intake, which could result in insufficient intake of essential nutrients, especially protein