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14 We should foster a culture of encouragement, empathy, and positive reinforcement

They added that while many of the studies are limited by small sample sizes, short follow-up and a lack of control groups, further study of these medications in PsA and RA are warranted

Mounjaro is used as part of a comprehensive medical weight management plan, which includes dietary and exercise interventions

Monitoring and Follow-Up Establish a structured monitoring schedule: Monthly visits during dose titration and the first 6 months Quarterly visits once stable, assessing weight, tolerability, and metabolic parameters Annual comprehensive evaluation including lipid panel, HbA1c (if diabetic), liver function tests, and cardiovascular risk assessment Regular monitoring allows early identification of plateaus, adverse effects, or emerging medical issues that may require intervention

By demonstrating protective effects in a ciliopathy model, this study suggests that GLP-1 RAs may confer benefits beyond appetite suppression in patients with genetic obesity syndromes affecting ciliary function, further broadening the mechanistic rationale for targeting this pathway across diverse genetic etiologies of obesity