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Liu Z, Wu C, Lin Z, Li H, Liu Y, Amjad N, et al

Of these, one provided data obtained from in vitro models of -glutamyl cycle metabolites, twenty nine provided data on metabolites and/or co-factors of the -glutamyl cycle or trans-sulphuration pathway, six provided the results of intervention studies, six included genetic data and eight studies provided data on enzyme activity

Clin Kidney J

While such models provide significant mechanistic insights into APAP-induced hepatotoxicity, including pathways related to oxidative stress, mitochondrial dysfunction, and inflammasome activation, they may not fully recapitulate the complexity of human physiology

Overall, our results showed that selenium deficiency is commonly associated with these medical conditions in a country with low selenium intake