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In addition to the physiological functions of protein-bound lipoic acid, there is increasing scientific and medical interest in potential therapeutic uses of pharmacological doses of free (unbound) lipoic acid (3)

Effects and mechanisms of berberine in diabetes treatment

Glutathione synthesis is essential for mouse development but not for cell growth in culture

Manach C, Scalbert A, Morand C, Remesy C, Jimenez L

We hypothesized that low glutathione redox status would be associated with elevated markers of oxidative protein and DNA damage, inflammation and mitochondrial superoxide production in two regions that have been reported to be abnormal in autism, cerebellum and BA22