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Under normal conditions, Nrf2 is anchored in the cell cytoplasm by a repressor protein called Keap1

Unlike many antioxidants that function primarily in either water- or fat-based environments, ALA works in both, allowing it to support antioxidant activity throughout the body.64 Research has also found that ALA may help regenerate other antioxidants, including vitamins C and E

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Other studies confirm this trend: for instance, proteinpolysaccharide Pickering particles also significantly improved -carotenes light stability relative to non-encapsulated carotene

In summary, viral persistence could play a major role in PASC, considering the ability of the SARS-CoV-2 pathogen to infect and reinfect individuals over a lifetime 274