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10.1038/s41593-022-01065-x 21
Experts say the drugs effects on dopamine signaling and brain inflammation could account for the benefits
Small levothyroxine adjustments (typically downward by 12.525 mcg) are sometimes needed, but changes are usually minor and made gradually based on lab results, not symptoms alone
Vitamins and minerals are important, but when they are taken by mouth the amount that can actually be absorbed and used is limited as they move through the intestines and are processed by the liver
Clinical trial data shows that burping rates vary by drug and dose: Ozempic injection (semaglutide): Burping reported in 3% of patients at the 0.5 mg dose and 1% of patients at the 1 mg dose Wegovy injection (semaglutide): Burping reported in 7% of adults at the 2.4 mg dose Mounjaro and Zepbound (tirzepatide): Burping reported in 25% of patients across doses (Source: Drugs.com) These numbers likely underestimate real-world prevalence, as sulfur burps are often underreported in clinical trials or described under broader terms like belching or eructation. Some patients avoid mentioning it to their doctors out of embarrassment, as well
