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eClinicalMedicine, 2025

Excessive B12, especially in supplement form, can cause mild digestive issues in some people

For example, Changpusan has demonstrated significant antidepressant effects in the CUMS model, with its impact on tryptophan metabolism confirmed through metabolomic profiling [547]

Clonidine is a centrally acting -adrenergic and imidazoline (I) receptor agonist that reduces central sympathetic outflow and norepinephrine release, resulting in decreased heart rate and peripheral vascular resistance