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If that number surprises you, it should reinforce why starting at just 5 units matters so much for building tolerance gradually
Each step usually involves a minimum four-week hold to assess tolerance before moving up
A 0.25mg starting dose at that concentration is 2.5 units at the edge of insulin-syringe measurement accuracy
Patients can ask Fridays support which pharmacy will fill their specific prescription
When to seek medical advice: Persistent vomiting preventing adequate fluid intake Severe abdominal pain Signs of pancreatitis (severe upper abdominal pain radiating to the back) Symptoms of thyroid problems (lump in neck, hoarseness, difficulty swallowing) Any side effect that significantly impacts quality of life According to NICE guidance, treatment should be reviewed if HbA1c targets are not achieved or if side effects prove intolerable despite management strategies
