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63, 64 Interestingly, the presence of proinflammatory cytokines and activated neuroglia have been reported in the autism cerebellum among other regions, 9 suggesting that activated neuroglia produce excess NO and may contribute to the peroxynitrite formation and increased 3-NT protein damage observed in the present study

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Koklesova, L

whether p53 acts upstream of these pathways, converges with them, or is modulated by them to exert its dual effects remains largely unexplored

1 This landmark study builds on more than 20 years of research in obesity, a serious chronic disease associated with severe co-morbidities and outcomes