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Despite the encouraging results of GLP-1/glucagon co-agonism in experimental models, different GLP-1 and glucagon co-agonists have shown various levels of efficacy and tolerability in people with obesity and/or T2D, in early phase clinical trials, which may be explained by the different ratio of GLP-1 to glucagon activity between the different molecules [65]

Glutathione acts as a skin-lightening agent, reducing dullness and creating a more youthful complexion

One trial measuring skin effects found that oral GSH (500 mg/day) led to modest improvement in skin appearance within 4 weeks

Each orange bar is a feeding and the height indicates the duration