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103 To combine gene therapy with anticancer drug delivery, chitosan functionalized magnetic graphene (CMG) NPs were synthesized 105 and reported that these biocompatible NPs were capable of releasing DOX under pH 5.1 at a higher rate than 7.4

Euthanasia was performed when tumor size reached this permitted maximum or if animals became moribund due to severe weight loss or unhealing ulceration

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