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The tumor volume in diabetic mice was the largest while TZP treatment significantly reduced CRC volume and weight in T2DM mice (Figure 3DF)
This study further demonstrated that exendin-4 treatment additionally reduced the presence of key inflammatory molecules, including TNF-alpha, interleukin 1 beta (IL-1beta), and IL-6, in mice livers [46], providing evidence for potential GLP-1 treatment for inflammation related to steatohepatitis
For many people this takes just a few weeks, and for others it may take a month or two
Knocking down ACTL6A had no impact on NRF2 expression (Supplementary Fig 6h)
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