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GLP-1 patches do not actually contain semaglutide or tirzepatide or any other of the active ingredients found in GLP-1 medications, nor are they FDA approved or proven to be effective

Marketed as Mounjaro for diabetes and Zepbound for weight management, tirzepatide offers a once-weekly injection option that addresses both glycemic control and weight reduction

However, it requires weekly injections and may cause gastrointestinal side effects

GLP-1 receptor activation affects vascular function, and changes in microvascular blood flow could alter how sensory nerves in the skin behave