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Inform your doctor if these side effects persist

Nausea affects roughly 25-40% of patients starting semaglutide therapy, particularly during the first month of treatment

Semaglutide targets specific areas in the brain that control hunger and fullness

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To identify IGF-1-mediated miRNA regulatory networks that cause temozolomide (TMZ) to be insensitive to glioblastoma multiforme treatment, on the basis of comprehensive analysis of multiple databases and in vitro experiments, Chen et al (104) confirmed that IGF-1 upregulated miR-513a-5p signaling reduced the sensitivity of glioma cells to TMZ by inhibiting the NEDD4L-inactivated Wnt/-catenin pathway