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The study also pointed out that only a small portion (less than 3%) of the participants were over age 75, and advised caution in prescribing for these populations

They were further washed in 100% methanol for 1 h and incubated overnight in 66% dichloromethane (DCM) and 33% methanol at room temperature

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The concept of a beyond-use date exists because compounded medications are prepared individually or in small batches