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Vulnerable populations such as frail patients, pregnant women, adolescents and the elderly may be more susceptible to adverse effects like muscle loss or nutritional deficits
Artificial overexpression of GPx1 showed an increased capacity to rescue breast cancer cells from the cell cycle arrest caused by hyperoxic stress, indicating the involvement of both peroxide-derived free radicals and nonperoxide-derived species during the deleterious process [84]
J Neuroinflammation 15(1):245 Jing F, Zhang Y, Long T, He W, Qin G, Zhang D, Chen L, Zhou J (2019) P2Y12 receptor mediates microglial activation via RhoA/ROCK pathway in the trigeminal nucleus caudalis in a mouse model of chronic migraine
8): (1) Pharmacokinetic enhancement: threefold higher bioavailability than BBR chloride (BCl2H2O) in db/db mice [200]
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