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Future research on tesamorelin may explore its broader applications beyond HIV-associated lipodystrophy, including its potential for age-related fat reduction, cognitive benefits, and metabolic disease management

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Overcoming these barriers necessitates a thorough comprehension of patient-specific elements influencing treatment response, advancements in prognostic methodologies such as machine learning, and a comprehensive approach to clinical oversight that integrates awareness, screening, diagnosis, treatment, and monitoring [42,43]

PLoS ONE (2010) 5:e12226

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