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Description

The gradual breakdown of extracellular matrix (ECM) is a hallmark of KOA (Loeser, 2017), which is caused by an imbalance of catabolic and anabolic signals in cartilage

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It is often due to trauma such as nail biting or onychocryptosis (Fig

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Stata J

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Allopurinol dose relative to renal function and risk of hypersensitivity reactions

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A consultation will determine if it is appropriate for you

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