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Research in humans is a bit less impressive Clinical trials in humans A 1981 double-blind study found that chronic insomniac patients found that subjects slept 59% more, shorter sleep latency, and higher sleep efficiency (Schneider 1981) A 1987 double-blind study did not find any statistically significant changes in sleep structure as measured by REM sleep, NREM sleep, or total sleep time (Debellis 1987) A 1992 double-blind study in 14 chronic insomnia patients found higher sleep efficiency and subjectively estimated tiredness decreased to similar levels of healthy subjects in 7 nights of injections (Schneider 1992) There are some limitations to these studies however

Cycles 2 and 3 typically show the most meaningful changes in body composition, sleep quality, and recovery

Diabetes Metab Syndr Obes 17:14251440

The researchers reported an even stronger association between increased testosterone and decreased omega-6 fatty acid concentration in red blood cell membranes

Patients in our practice often report improvement in pain and mobility within the first few weeks, and our protocols typically run four to eight weeks