Yes, they can be associated with nutritional deficiencies, especially low protein intake, vitamin D deficiency, thiamine and other B-vitamin deficits, iron depletion, and low intake of minerals such as calcium, magnesium, and potassium
these actions are largely centrally mediated because GDF15 binds to its receptor, the glial cell line-derived neurotrophic factor family receptor alpha-like (GFRAL), which is localised in the hindbrain and hypothalamus [57,58,59]
Zepbound, clinically known as tirzepatide, is a medication primarily for adults who struggle with obesity or excess weight linked to weight related medical issues
Duarte C, Pinto-Gouveia J, Ferreira C
The body then enters ketosis a metabolic state where the body burns fat for energy