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While studies in animal models have shown promising results, more research in humans is needed to determine its safety for treating arthritis

Besides, it stimulated expression of early growth response 1 (egr-1) gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1-A binding protein-2 (nab2)) (44)

These two seem to go hand in hand so if you deal with one of them the other has a reciprocal reaction

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Paracas Peninsula Tour, the most important wildlife sanctuary on the Peruvian coast