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The participants median age was 66, and the median follow up was 5 years

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Patients were randomized to receive final doses of 30 mg, 50 mg, or 70 mg of VYVANSE or placebo once daily in the morning for a total of four weeks of treatment

A second important limitation relates to the substantial heterogeneity observed across studies

Menstrual changes that have been anecdotally reported include: Irregular cycle timing or missed periods Heavier or lighter menstrual flow Changes in premenstrual symptoms Breakthrough bleeding between periods It is important to note that there is no official direct link established between tirzepatide's pharmacological mechanism and menstrual function