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Examined biomarkers, serum selenium and enzymatic activity of glutathione peroxidase (GPX activity), were significantly lower in participants without meat in their diet (Figure 1)

Studies document effects on 31.2% of human genes (approximately 4,000+ genes) with 50% expression change, suppressing RNA production in 70% of 54 genes overexpressed in metastatic colon cancer

Research Administration and Dosing Considerations Published research on BPC-157 in animal models has used various administration routes: Intraperitoneal injection: Common in rodent studies but impractical for veterinary application Subcutaneous injection: More relevant to potential veterinary use Intramuscular injection: Studied in some larger animal models Oral administration: Some research suggests oral bioavailability, though data is limited Topical application: Investigated for wound healing applications Dosing in animal studies varies widely (typically reported as g/kg body weight), and optimal dosing for dogs specifically has not been established through controlled veterinary trials

Product Facts Supplement Facts Serving Size 1 Veggie Capsule Servings Per Container 60 *Daily Value not established

doi: 10.1007/s12672-025-03629-2 27 KamedaKYanagiyaRMiyatakeYCarrerasJHiguchiHMurayamaHet al