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By directly binding RAF-1 and MEK, RKIP interferes with the formation of the kinase-substrate complex, thereby inhibiting the phosphorylation of MEK, ultimately plays a role in inhibiting RAF/MEK/ERK signaling pathway

The mRNA expressions of PECK1 and G6Pa , which are key gluconeogenesis-related genes, were significantly upregulated by dietary L-carnitine in the liver, but did not change in the muscle (Fig

For now, Shungu is focusing heavily on an oxidative stress model

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