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A 2006 Achilles-detachment study by Krivic and colleagues in the same journal applied BPC-157 intraperitoneally once daily at 10 g/kg, 10 ng/kg, or 10 pg/kg for 30 days in rats and reported that tendon-to-bone tissue, which did not heal spontaneously in saline controls, recovered with BPC-157 treatment, with directionally improved load-to-failure, stiffness, Young's modulus, and collagen organization at days 121, including in animals where healing had been impaired by 1 mg/kg 6-methylprednisolone though the abstract does not report numeric effect sizes or p-values
This matters most for tendons, which are naturally avascular and heal slowly under baseline conditions
Why Are BPC-157 and TB-500 Often Discussed Together
KPV (Lysine-Proline-Valine Tripeptide): Compound Type: Tripeptide (Lys-Pro-Val)
Boonyaritichaikij S, Kuwabara K, Nagano J, Kobayashi K, Koga Y (2009) Long-term administration of probiotics to asymptomatic pre-school children for either the eradication or the prevention of Helicobacter pylori infection
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