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Further studies are also needed to assess mechanistic insights into GLP-1RAs on CV parameters and clinical safety of GLP-1RAs especially in elderly populations

The study recruited 411 patients and showed that danuglipron reduced glycated hemoglobin, fasting blood glucose and body weight at week 16 compared with placebo and was well tolerated without the need for injections or fasting restrictions (Saxena et al., 2023)

Improving gut health doesnt have to be extreme

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Lustig RH, Mulligan K, Noworolski S, Gugliucci A, Erkin-Cakmak A, Wen MJ, Tai VW, Schwarz JM: Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome